8:00 am Check-In & Morning Coffee

8:50 am Chair’s Opening Remarks

2024 Industry Analysis: Leveraging Different Spatial Technologies

9:00 am Panel: Addressing Common & Diverse Challenges in Adopting & Implementing Spatial Technologies Across Drug Development

  • Lauri Diehl Pathologist, Gilead Sciences
  • Shih-Ying Wu Senior Advisor - Data Science & Bioinformatics, Eli Lilly & Co.
  • Ben Chen Scientific Senior Director, Lab Head for Solid Tumor Translational Medicine Research, BMS

Synopsis

  • Understanding how industry experts select the right spatial biology tool for their study, be it based on disease indication, modality, stage within the pharma value chain or other criteria
  • Soundboarding ideas to overcome barriers to internal entry including cost, time and hesitancy to adopt new technology
  • Why are some pathologists more receptive to new enabling technologies like spatial technologies?

9:45 am Session Reserved For Roche

10:15 am Morning Break & Speed Networking

Synopsis

As the Spatial Biology community is reunited, this valuable session will ensure you get the chance to reconnect with peers and make brand new connections! This structured networking opportunity will pair you with fellow attendees for several 3-minute introductions, ensuring you have the opportunity to meet and network with your academic and industry colleagues!

Integrating Different Spatial Technologies to Empower Drug Discovery & Development Workflows

11:15 am Enhancing Targeted Therapeutics with Spatial Biology

  • Tom Turi Chief Scientific Officer, Flagship Biosciences

Synopsis

  • Innovative methods in biomarker discovery utilizing spatial biology
  • Leveraging spatial biology to advance the development of antibody-drug conjugates (ADCs)
  • Integrating spatial biology techniques to improve patient-specific treatment strategies

11:45 am Spotlighting Strategies to Integrate Single-Cell & Spatial Biology to Support Drug Discovery

Synopsis

  • Combining spatial technologies using in vivo and ex vivo samples to better understand disease biology from oncology to immunology
  • Integrating single-cell technology with spatial biology techniques to support more accurate target identification and validation
  • Discussing how this spatial information and platforms could be used to empower downstream drug discovery and development

12:15 pm Session Reserved For Nucleai

12:45 pm Session Reserved for PredXBio

1:15 pm Lunch & Networking

Applications Of Spatial Biology Across Different Stages of Drug Development & Different Indications

2:15 pm Leveraging Spatial Multiplex Imaging to Improve Translational Research for Solid Tumor Studies

  • Pei-Hsuan Chen Continuous Improvement Specialist & Continuous Improvement Manager Translational Biology, BMS

Synopsis

  • Exploring the application of multiplex spatial imaging platforms in solid tumor research
  • Utilizing spatial biology techniques to uncover predictive biomarkers for approved drugs across different indications
  • Leveraging this data to refine patient stratification methods and enhance the design of future clinical trials for improved treatment outcomes 

2:45 pm Session Reserved For UIltivue

3:15 pm Uncover the Mechanism for Reproductive Toxicology: The Application of Spatial Transcriptomics in Drug Discovery

Synopsis

  • Utilizing spatial transcriptomics to understand drug treatment induced developmental issues
  • Analysis of pipeline development for the comparison of spatial transcriptomics data across two groups of samples
  • Further analyze the impact of differentially expressed genes on embryo development

3:45 pm Harnessing Multimodal Data to Power Successful Therapies: AI Driven Insights from Target ID to Patient Selection

Synopsis

  • Modern advances in high-parameter spatial biology and machine learning hold immense promise to accelerate biological research and transform our understanding of complex tissues in health and diseases; however, unlocking actionable insights from these biological datasets remains challenging due to siloed infrastructure and storage, static tools and interoperability, and historically single-use data generation
  • Enable Medicine has built a complete data-to-insights platform for targeted biological discovery, bridging the most comprehensive cloud biodata infrastructure with best-in-class AI/ML research and spatial methods to generate, index, and annotate multi-omic data
  • Learn how the Enable Medicine Platform empowers high-value drug research and development, including target identification or prioritization, patient stratification, and indication selection

4:15 pm Afternoon & Networking Break

Sharing Best Practices of Using Spatial Technologies to Supercharge Non-Oncology Drug Development

5:15 pm Uncovering How to Leverage Spatial Tools to Better Support Immunology Research

  • SILVIA SISO SENIOR PRINCIPAL RESEARCH SCIENTIST-PATHOLOGIST, Abbvie

Synopsis

  • Understanding the rationale behind the study design to inform target identification
  • Sharing optimized strategies to ensure good sample quality
  • Linking the information from spatial biology to improve immune-related disease research or drug development

5:45 pm Enhancing Biologics Drug Development Across Multiple Disease Indications Through Spatial Biology

Synopsis

  • Examining the strategic integration of spatial biology beyond biomarker discovery in biologics drug development across cardiovascular, neurological and metabolic disease
  • Assessing the broader applications of spatial biology techniques in shaping the overall strategy of drug development
  • Exploring the impact of leveraging spatial biology approaches to unlock new avenues for therapeutic innovation in large molecules including ADCs and complex multifunctional molecules 

6:15 pm Chair’s Closing Remarks