Spatial Multi-Omics of Crohn’s Disease: Advancing Pathobiology & Target Discovery in Biopharma
Time: 9:00 am
day: Day Two
Details:
- Highlighting the application of cutting-edge spatial omics technologies – including spatial transcriptomics, single-nucleus RNA sequencing, and high-order multiplexed protein imaging – to study the complex pathobiology of Crohn’s disease using FFPE tissue
- Integrating spatial and single-cell data with histological annotation, we reveal distinct epithelial states, immune-stromal interactions, and ulcer-associated transcriptional programs that inform therapeutic hypothesis generation
- Harnessing this multi-omics approach enables high-resolution, spatially contextualized insights directly from archived clinical samples, offering a powerful platform for target discovery and translational research in chronic inflammatory diseases
