Conference Day One | Wednesday, October 22, 2025
7:50 am Check In & Light Breakfast
8:50 am Chair’s Opening Remarks
Driving Reproducibility Across Spatial Platforms & Sites Enabling Widespread Spatial Biology Adoption
9:00 am Boosting Reproducibility & Standardization to Drive Real-World Spatial Biology Adoption
Synopsis
- Overcoming the practical challenges of generating reproducible spatial data across sites, timepoints, and platforms, and why this is crucial for real translational impact
- Aligning workflows and performance criteria to build confidence in spatial assays, from tissue handling to image analysis and interpretation
- Accelerating the journey from pilot projects to everyday adoption by addressing the bottlenecks that hold back scalable, deployable biomarkers in pharma pipelines
9:30 am From Discovery to Impact: Spatial Biology as a Translational Enabler
Synopsis
- Emerging spatial data modalities are driving a paradigm shift in how cancer research and disease understanding are approached
- Spatial technologies are increasingly considered within clinical trials to enhance decision-making and patient outcomes
- Exploring the future of spatial biology and what’s needed to expand its impact from discovery through to the clinic
10:30 am Panel Discussion: What Will it Take to Standardize Spatial Across Industry & Who Should Lead the Charge?
Synopsis
- What are the most critical barriers currently preventing standardization across spatial platforms, workflows, and datasets in biopharma?
- How do inconsistent tissue handling, assay protocols, and data formats affect cross-study comparability and regulatory acceptance?
- Should standardization start with biomarkers, instrumentation, data pipelines, or all at once? What should the priority be?
11:00 am Morning Refreshments & Speed Networking
Synopsis
Kick off your Summit experience by building valuable new connections across the spatial biology community. This interactive session is designed to help you quickly meet peers tackling similar challenges in spatial technologies, multi-omics integration, and translational implementation, sparking conversations and collaborations that last well beyond the Summit.
Unlocking Spatial Insights to Drive Mechanistic Understanding & Target Discovery to Catalyse Novel Therapeutic Breakthroughs
12:00 pm Decoding Multicellular Interactions in the Tumor Microenvironment using Integrated Spatial Multi-Omics
Synopsis
- Harnessing advanced computational pipelines and spatial experimental methods to resolve cell–cell interactions in situ at high resolution
- Integrating same-section multi-omics (transcriptomics & proteomics) for an unbiased view of the tumour microenvironment and resistance mechanisms
- Applying target-agnostic spatial proteomics to uncover novel biomarkers and cellular neighbourhoods driving treatment failure and progression
12:30 pm Reserved for Ultivue
Synopsis
Session Details to be Revealed
1:00 pm Leveraging Spatial Biology for ADC Design & Target Characterization
Synopsis
- Using spatial biology to interpret preclinical models
- Changing ADC design parameters based on spatial biology feedback
- Relating target localization to other preclinical data to validate preclinical hypotheses
1:30 pm Lunch Networking Break
Selecting the Right Tools, Technologies & Partners to De-Risk Implementation & Accelerate Better Drugs Reaching Patients
2:30 pm Rewiring R&D for Precision Medicine: Enhancing Translational Success with Biomarkers, Partnerships, & Spatial Biology
Synopsis
- Exploring how using biomarkers and spatial biology platforms earlier in R&D can overcome translational hurdles, improve target validation, refine patient stratification, and provide early response signals through cellular and regional insights
- Highlighting how partnerships across industry, academia, philanthropy, and public agencies can enable foundational research, support better stratification, and build shared biomarker platforms for scalable, reproducible precision R&D
- Discussing why disease-specific frameworks are needed beyond oncology to tackle different mechanisms, biomarker access, and endpoint challenges, particularly in areas such as psychiatry and neurodegeneration
3:00 pm Reserved for Flagship Biosciences
Synopsis
Session Details to be Revealed
3:10 pm Roundtable Discussion: Building Better Partnerships for Robust Results to Unlock Scalable Spatial Biology
Synopsis
- Defining what makes an effective spatial biology partner to ensure robust, reproducible results
- Setting clear standards for workflows, data sharing, and validation to ensure reproducibility and trust
- Building long-term frameworks for cross-functional collaboration that drive adoption and real-world impact
3:45 pm Afternoon Networking & Poster Session
Synopsis
Join the spatial biology community for an interactive session exploring pioneering research, breakthrough technologies, and real-world solutions. Share your work, exchange ideas, connect with peers, and help shape the future of spatial biology in drug development. See full T&Cs online for eligibility.
Overcoming Critical Data Infrastructure & Analysis Challenges to Support High-Dimensional Spatial Workflows to Drive Unprecedented Disease Understanding
4:45 pm Generating High-Quality Spatial Multi-Omic Data: Experimental Strategies to Enable Meaningful Discovery in Oncology Research
Synopsis
- How can experimental design be optimized to improve multi-omics spatial data outputs?
- What lessons can be learned from high-quality case studies in oncology applications?
- How does cross-platform integration strengthen target discovery and patient stratification?
5:15 pm Underpinning the Transformative Potential of Spatial Omics in Toxicologic Pathology
Synopsis
- Considering the preanalytical variables that can influence the quality and reproducibility of spatial omics data
- Exploring how spatial omics can be applied effectively in preclinical species to generate meaningful insights
- Highlighting the vital role of pathologists in designing, conducting, and interpreting spatial omics experiments