7:15 am Check-In & Morning Coffee
7:55 am Chair’s Opening Remarks
2024 Industry Analysis: Leveraging Different Spatial Technologies
8:00 am Panel: Addressing Common & Diverse Challenges in Adopting & Implementing Spatial Technologies Across Drug Development
Synopsis
- Understanding how industry experts select the right spatial biology tool for their study, be it based on disease indication, modality, stage within the pharma value chain or other criteria
- Soundboarding ideas to overcome barriers to internal entry including cost, time and hesitancy to adopt new technology
- Why are some pathologists more receptive to new enabling technologies like spatial technologies?
8:45 am AI 101: Understanding the Basics of Responsible AI Development for Applications in Digital Pathology
9:15 am Morning Break & Speed Networking
Synopsis
As the Spatial Biology community is reunited, this valuable session will ensure you get the chance to reconnect with peers and make brand new connections! This structured networking opportunity will pair you with fellow attendees for several 3-minute introductions, ensuring you have the opportunity to meet and network with your academic and industry colleagues!
Integrating Different Spatial Technologies to Empower Drug Discovery & Development Workflows
10:15 am Enhancing Targeted Therapeutics with Spatial Biology
Synopsis
- Innovative methods in biomarker discovery utilizing spatial biology
- Leveraging spatial biology to advance the development of antibody-drug conjugates (ADCs)
- Integrating spatial biology techniques to improve patient-specific treatment strategies
10:45 am Spotlighting Strategies to Integrate Single-Cell & Spatial Biology to Support Drug Discovery
Synopsis
- Combining spatial technologies using in vivo and ex vivo samples to better understand disease biology from oncology to immunology
- Integrating single-cell technology with spatial biology techniques to support more accurate target identification and validation
- Discussing how this spatial information and platforms could be used to empower downstream drug discovery and development
11:15 am SpaceIQ™: Revealing New Mechanisms of Action Harnessing Spatial MultiOmics Powered by Spatial Computing
Synopsis
- Revealing hidden pathways and interactions beyond genomics in the tumor microenvironment with SpaceIQ
- Using Explainable AI to analyze spatial relationships between immune cells and tumor cells to enhance immunotherapy effectiveness
- Leveraging AI-driven spatial biomarker insights to uncover mechanisms driving immune evasion and cancer progression
11:45 am Lunch & Networking
12:45 pm Enabling Spatial Data-Driven Decision Making to Increase Success Rates for Next-Gen Therapeutics: A Framework For AI-Spatial Intelligence
Synopsis
- Identifying novel spatial biomarkers across imaging modalities for portfolio prioritization/ positioning
- Modeling the bystander effect of ADCs drug delivery within the tumor microenvironment for biomarker validation & patient selection
- Patient selection for prospective trials using AI-augmented biomarker scoring and quantification
Applications Of Spatial Biology Across Different Stages of Drug Development & Different Indications
1:15 pm Leveraging Spatial Multiplex Imaging to Improve Translational Research for Solid Tumor Studies
Synopsis
- Exploring the application of multiplex spatial imaging platforms in solid tumor research
- Utilizing spatial biology techniques to uncover predictive biomarkers for approved drugs across different indications
- Leveraging this data to refine patient stratification methods and enhance the design of future clinical trials for improved treatment outcomes
1:45 pm Session Reserved For UIltivue
2:15 pm Uncover the Mechanism for Reproductive Toxicology: The Application of Spatial Transcriptomics in Drug Discovery
Synopsis
- Utilizing spatial transcriptomics to understand drug treatment induced developmental issues
- Analysis of pipeline development for the comparison of spatial transcriptomics data across two groups of samples
- Further analyze the impact of differentially expressed genes on embryo development
2:45 pm Afternoon & Networking Break
3:30 pm Harnessing Multimodal Data to Power Successful Therapies: AI Driven Insights from Target ID to Patient Selection
Synopsis
- Modern advances in high-parameter spatial biology and machine learning hold immense promise to accelerate biological research and transform our understanding of complex tissues in health and diseases; however, unlocking actionable insights from these biological datasets remains challenging due to siloed infrastructure and storage, static tools and interoperability, and historically single-use data generation
- Enable Medicine has built a complete data-to-insights platform for targeted biological discovery, bridging the most comprehensive cloud biodata infrastructure with best-in-class AI/ML research and spatial methods to generate, index, and annotate multi-omic data
- Learn how the Enable Medicine Platform empowers high-value drug research and development, including target identification or prioritization, patient stratification, and indication selection
Sharing Best Practices of Using Spatial Technologies to Supercharge Non-Oncology Drug Development
4:00 pm Uncovering How to Leverage Spatial Tools to Better Support Immunology Research
Synopsis
- Understanding the rationale behind the study design to inform target identification
- Sharing optimized strategies to ensure good sample quality
- Linking the information from spatial biology to improve immune-related disease research or drug development